There are many kinds of medicines, and if they are classified by physical state, they can be divided into solid, semi-solid, liquid and gas dosage forms. Among them, solid preparations account for about 70% of all medicines, and are the main dosage forms of medicines. They have the advantages of good physical and chemical stability, low production and manufacturing costs, and easy to take and carry. Therefore, they are well received by patients.
It is worth mentioning that although the advantages of the new granulation process are prominent, the key to whether the new process equipment can be used normally is the key to the success or failure of debugging. Many users reported that the above-mentioned wet granulation and boiling drying equipment often have quality problems such as "too many feeds" during the debugging process, which seriously affects the granulation effect.
In order to solve the quality problems such as "too many feeds" in the trial production and commissioning, some domestic manufacturers have also started from the working principles of wet granulation and boiling drying, combined with the traditional granulation process, and carried out experimental analysis and discussion on boiling drying. Commissioning of the new wet granulation and boiling drying equipment, and improvements were made to the problems that occurred during the commissioning of the equipment.
There are also companies that have designed a wet granulation boiling and drying in-line unit through extensive absorption and combination of domestic and foreign solid preparation production process characteristics, which are wet granulator, boiling dryer, dry granulator, The material conveying, mixer, etc. are effectively combined, and the new model is developed according to the actual production demand worldwide. The structure is reasonable and the performance is stable. It also avoids the problem of "too many materials", and is suitable for the previous process such as tablets and capsules. and the production of granules
In general, under the background of increasing aging and consumption upgrading, the market demand for solid pharmaceutical preparations will also continue to grow. Pharmaceutical equipment also needs to keep pace with the times and constantly upgrade to meet the production requirements of higher quality products.